Reducing Post-Procedure Bleeding in Endoscopic Mucosal Resections (EMR)


Post-procedural bleeding occurs in 5-10% of endoscopic mucosal resections (EMR) of large colorectal polyps.1 Published in 2019, a multi-center randomized trial found that clip closure of the EMR mucosal defect significantly reduced post-procedure bleeding. The location of the polyp also impacted the risk of bleeding, as noted in the graph shown below.1 

RCT: 919 patients with ≥20 mm
non-pedunculated colorectal polyps


When choosing a hemostatic clip, physicians are seeking durability and maneuverability. In recent testing, CONMED’s DuraClip® showed a 46% higher compression force than Boston Revolution 360.2

Greater compression force offers several benefits and enables physicians to close defects with confidence. Sometimes there is a perception that to achieve higher closure force, a larger clip or a clip with a larger stem is needed. But this isn’t always the case. DuraClip®’s higher closure force is credited to its scissor style open/close mechanism and rigid jaws. Dr. Moamen Gabr, Director of Endoluminal Surgery at Beth Israel Deaconess Med Center, has experienced this firsthand.

“I use DuraClip® for many reasons. Its ease of rotation is important, especially when performing closures. Also, at the end of a POEM or after an EMR, you’re using multiple clips to perform mucosa-to-mucosa closure. That can be cumbersome if you have a long stem clip blocking your field of vision. It’s very helpful when you have a short arm that does not block your view.”

DuraClip® is one of the smallest clips on the market, offering up to a 60% shorter post-deployed stem than Boston Resolution 360.2

Dr. Andy Tau, Austin Gastroenterology, uses DuraClip® in his practice because of its maneuverability.

“DuraClip® is able to pass through a scope in full retroflexion. No other clip can do so”, he shared.

If you’re treating resections that lead to large defects, don’t leave your closure to chance. Choose DuraClip® for the durability and precision your patients deserve. LEARN MORE


1 Pohl H, Grimm IS, Moyer MT, Hasan MK, Pleskow D, Elmunzer BJ, Khashab MA, Sanaei O, Al-Kawas FH, Gordon SR, Mathew A, Levenick JM, Aslanian HR, Antaki F, von Renteln D, Crockett SD, Rastogi A, Gill JA, Law RJ, Elias PA, Pellise M, Wallace MB, Mackenzie TA, Rex DK. Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial. Gastroenterology. 2019 Oct;157(4):977-984.e3. doi: 10.1053/j.gastro.2019.03.019. Epub 2019 Mar 15. PMID: 30885778; PMCID: PMC8224988.

2 Data on file comparing DuraClip® 11mm to Boston Revolution 360: PDD2324060.